Systems Biology (Cell Engineering)

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Jonathan Silva Assistant Professor. Michael Vahey Assistant Professor. Kareem Azab - Radiation Drug delivery, polymer conjugates, nanoparticles, lyposomes, targeted therapy, biodegradable polymeric emplants, medical devices, pharmaceutical sciences. Randall Bateman - Neurology Diagnostic clinical test biochemistry mass spectrometry process robotics Alzheimer's disease neurodegeneration.

Reprogramming cellular behavior and engineering cell fate

Barak Cohen - Genetics Evolution of complex traits; synthetic biology for engineering gene expression. Farshid Guilak - Orthopaedic Surgery biomechanics, tissue engineering, regenerative medicine, osteoarthritis, synthetic biology, stem cells, mechanobiology, mechanotransduction, cell mechanics. Edward Han - Neuroscience Two-photon calcium imaging, electrophysiology, virtual reality behavior, neuronal networks, learning and memory, hippocampus.

Vitaly Klyachko, PhD Synaptic function and plasticity; neural circuits; information analysis; neurological disorders. Christopher Lingle - Anesthesiology Basic Science Research ion channel biophysics, modeling of channel gating and cell excitability, methods of analysis.

Jeffrey Milbrandt, MD, PhD - Genetics functional genomics, metabolic pathway, mitochondria, nerve regeneration, neurodegeneration, transcriptional networks. Robi Mitra - Genetics Genomics. Using synthetic biology, scientists are testing models of how biology works by building systems based on models and measuring differences between expectation and observation.

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Second, the idea arose that, to some, biology is an extension of chemistry and thus synthetic biology is an extension of synthetic chemistry. Attempts to manipulate living systems at the molecular level will likely lead to a better understanding, and new types, of biological components and systems. Third is the concept that natural living systems have evolved to continue to exist, rather than being optimized for human understanding and intention. By thoughtfully redesigning natural living systems it is possible to simultaneously test our current understanding, and may become possible to implement engineered systems that are easier to study and interact with.

Fourth, the idea emerged that biology can be used as a technology, and that biotechnology can be broadly redefined to include the engineering of integrated biological systems for the purposes of processing information, producing energy, manufacturing chemicals, and fabricating materials.

Synthetic Biology: Programming Living Bacteria - Christopher Voigt

While the emergence of the discipline of synthetic biology is motivated by these agendas, progress towards synthetic biology has only been made practical by the more recent advent of two foundational technologies, DNA sequencing and synthesis. Sequencing has increased our understanding of the components and organization of natural biological systems and synthesis has provided the ability to begin to test the designs of new, synthetic biological parts and systems. While these examples each individually demonstrate the incredible potential of synthetic biology, they also illustrate that many foundational scientific and engineering challenges must be solved in order to make the engineering of biology routine.

Progress on these foundational challenges requires the work of many investigators via a coordinated and constructive international effort. Juan Enriquez: Using biology to rethink the energy challenge Juan Enriquez challenges our definition of bioenergy. Oil, coal, gas and other hydrocarbons are not chemical but biological products, based on plant matter — and thus, growable. Our whole approach to fuel, he argues, needs to change. George Church — Regenesis: How Synthetic Biology Will Reinvent Nature and Ourselves Regenesis provides a fascinating overview of synthetic biology and the wonders it can produce: from new drugs and vaccines to biofuels and resurrected wooly mammoths.

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Current Developments in Biotechnology and Bioengineering - 1st Edition

Recounting the evolution of life forms from the Hadean geologic era 3. With biotech hobbyists now at work in garages, the authors also urge the establishment of safety measures to keep people safe and engineered organisms under control. Andrew Hessel — Introduction to Synthetic Biology Andrew Hessel, pioneer in synthetic biology, discusses the similarities between computing and biology during a talk at Singularity University. Suzanne Lee: Grow your own clothes Designer Suzanne Lee shares her experiments in growing a kombucha-based material that can be used like fabric or vegetable leather to make clothing.

Stewart Brand: The dawn of de-extinction. Are you ready? But now, we have the technology and the biology to bring back species that humanity wiped out.

Systems & Engineering Approaches to Cancer

Joel Kostka. Professor and Associate Chair of Research. Georgia Tech School of Biology. David N. Lawrence P. Huang Chair in Engineering and Entrepreneurship. Julia M.


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Gabe A. Hang Lu. Nael McCarty. Marcus Professor of Cystic Fibrosis. Emory University.

The emerging role of systems biology for engineering protein production in CHO cells.

John F. Patrick T. Larry McIntire. Department Chair Emeritus. Julien Meaud. Annalise B. Muralidhar Padala.

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Emory Department of Surgery. Manu O. Boris I. Peng Qiu. Amit R. Fatih Sarioglu. Minoru Shinohara.